WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID.
The second row lists the following statistics:
Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:KEGG pathway       Name:VEGF signaling pathway       ID:04370
C=76; O=2; E=0.05; R=40.53; rawP=0.0011; adjP=0.0064
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000089159 NA PXN paxillin 5829 ENSG00000089159
2  ENSG00000164867 NA NOS3 nitric oxide synthase 3 (endothelial cell) 4846 ENSG00000164867


Database:KEGG pathway       Name:Leukocyte transendothelial migration       ID:04670
C=116; O=2; E=0.08; R=26.56; rawP=0.0026; adjP=0.0064
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000149564 NA ESAM endothelial cell adhesion molecule 90952 ENSG00000149564
2  ENSG00000089159 NA PXN paxillin 5829 ENSG00000089159


Database:KEGG pathway       Name:Axon guidance       ID:04360
C=129; O=2; E=0.08; R=23.88; rawP=0.0032; adjP=0.0064
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000001617 NA SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 6405 ENSG00000001617
2  ENSG00000196411 NA EPHB4 EPH receptor B4 2050 ENSG00000196411


Database:KEGG pathway       Name:Neuroactive ligand-receptor interaction       ID:04080
C=272; O=2; E=0.18; R=11.33; rawP=0.0134; adjP=0.0161
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000127533 NA F2RL3 coagulation factor II (thrombin) receptor-like 3 9002 ENSG00000127533
2  ENSG00000182162 NA P2RY8 purinergic receptor P2Y, G-protein coupled, 8 286530 ENSG00000182162


Database:KEGG pathway       Name:Cytokine-cytokine receptor interaction       ID:04060
C=265; O=2; E=0.17; R=11.62; rawP=0.0128; adjP=0.0161
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000104689 NA TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 8797 ENSG00000104689
2  ENSG00000163083 NA INHBB inhibin, beta B 3625 ENSG00000163083


Database:KEGG pathway       Name:Metabolic pathways       ID:01100
C=1130; O=3; E=0.73; R=4.09; rawP=0.0361; adjP=0.0361
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000121039 NA RDH10 retinol dehydrogenase 10 (all-trans) 157506 ENSG00000121039
2  ENSG00000164867 NA NOS3 nitric oxide synthase 3 (endothelial cell) 4846 ENSG00000164867
3  ENSG00000174951 NA FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2523 ENSG00000174951




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).